Total Herb Solutions USA / America, Ayurvedic Analytical Laboratory, Ayurvedic research lab
Heavy metals testing in herbals,stability testing of nutraceuticals,dietary supplements, Ayurveda, Ayurvedic, Botanical, Plant Extract

Because of complexity of the chemical composition, the analysis of herbal drug is the major problem in the development of the herbal drug industry. THS is first and unique of its kind in the country to establish exclusive herbal drug testing facility in Mumbai. In order to ensure quality of final product herbals has to go through battery of quality control parameters. A proper integration of physical, chemical, microbial, spectral and chromatographic analysis will ensure proper analysis of herbals. The organization is established to cater the herbal drug standardization need comprising of organoleptic, microscopical, physical, chemical, chromatographic testing, metal and aflatoxin contamination, etc. The laboratory is fully equipped with modern instrument and availability of more than 50 marker compounds, skilled and appropriately trained technical manpower.

  • Physicochemical analysis : Ash values, extractive values, moisture content, density, viscosity, surface tension, optical rotation, congealing point, etc.
  • Phytochemical analysis : Qualitative as well as quantitative determination of various class of primary (carbohydrates, lipids, proteins, etc.) as well as secondary (alkaloids, glycosides, saponins, flavanoids, coumarins, terpenoids, tannins, etc.) metabolites.
  • Microbial analysis : Total bioload, pathogens, etc.
  • Heavy metal analysis : By AAS
  • Aflatoxins analysis : B1, B2, G1, G2.
  • Toxicity : Acute and sub acute.

Physicochemical analysis : Often plays important role in herbal drug standardization. These tests are simple and quick to perform and give valuable information about the nature and purity of a drug. Some of the parameters like ash values indicate about the care being taken up while preparing the drug for commerce and extractive values possibly will be useful for selection of solvents for extraction. The tests which are normally performed include ash values, extractive values, moisture content, density, viscosity, surface tension, optical rotation, congealing point, volatile content, refractive index, solubility, swelling factor, etc.

We use IP, USP/NF, EP, JP, BP, AOAC and ACS compendia methods for raw material and final product testing.
                                                                                                                                                                          

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Botanical research lab, Botanical Analytical Laboratory, R & D Botanical
Plant Extract research lab, Plant extract Analytical Laboratory, R & D Plant Extract
Herbal heavy metal, Dietary supplement analysis, testing, lab, laboratories,research center
 

Phytochemical analysis : The activity of any herb is dependent on the class of phytoconstituents or specific phytoconstituents being present in it. In majority of the herbals which are in use the knowledge about these is fairly known. Therefore it is necessary to devise method of standardization based upon the presence of these chemicals. These chemicals are broadly categorized into two groups’ viz. Product of primary metabolites (carbohydrates, lipids, proteins, etc.) and secondary metabolites (alkaloids, glycosides, saponins, flavanoids, coumarins, terpenoids, tannins, etc.). Our phytochemical laboratory is well equipped to undertake both qualitative and quantitative evaluation of these constituents either as class or individual.

THS Laboratory test's botanical/herbal/nutraceutical products with widely accepted methods including those recommended by Indian Pharmacopeia, Indian Herbal Pharmacopeia, United States Pharmacopeia (USP), Herbal Compendium, China Pharmacopoeia, or other professional scientific organizations, or "in-House" methods to match your new discoveries of herbs or herbal extracts.

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  Evaluation of following parameters are carried out at THS

  • Microbial analysis
  • Heavy metal analysis
  • Aflatoxins analysis

Microbial bioburden studies : Medicinal plant materials normally carry a great number of bacteria and moulds often of soil origin. Amongst a large range of bacteria and fungi from the naturally occurring microflora of herbs, aerobic spore forming bacteria frequently predominate. Current practices of harvesting, handling and production often cause additional contamination and microbial growth. Some of the pathogenic bacteria seen in plant material are Escherichia coli, Salmonella typhimurium, Pseudomonas aeruginosa,Staphylococcus aureus.

A full-fledged microbiology section exists for testing bacterial and fungal contamination of herbal material with sterile testing facilities (Laminar flow hood). Anti microbial tests and a time saving and economical bioassay method using brine shrimps for evaluating biological activity of the herbal medicines are carried out for a preliminary screening of drugs. We also undertake Preservative Challenge, Bioburden, Assays, Sterility of herbal products.

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Heavy metal analysis : An essential step in plant material analysis is the determination of heavy metals. Presence of heavy metals like lead, arsenic, mercury etc. can be attributed to many causes such as environmental pollution and traces of pesticides.

Determination of heavy metals is carried out with the help of Atomic Absorption Spectrometry at THS.

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Animal studies: We at THS undertake systematic animal studies of herbal extracts and formulations by utilizing appropriate models.

Toxicity : Recent adverse events have clearly shown that all Herbal products are not free from side effects and toxicity. Products that have been confirmed to have bioefficacy can then be taken up for safety studies to determine possible side effects, adverse reactions and the maximum tolerable dosages. We undertake acute, sub-acute and chronic toxicity studies in animals.

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